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Plague Inc: Evolved official game artwork

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Plague Inc: Evolved Wiki

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadl

Steam ↗Windows · macOS · Linux
GameWiki EditorialReviewed 5 guide topics

GET YOUR BEARINGS

About Plague Inc: Evolved

Plague Inc: Evolved blends high‑level strategy with a realistic pandemic simulation. Starting from a single infected host, you evolve a pathogen to wipe out humanity while countering global defenses. The PC version adds multiplayer, user‑generated content, and enhanced 3D graphics.

The game features ten disease types, twenty‑three scenarios, and tools for creating custom content via Steam Workshop. Modes include competitive PvP, cooperative co‑op, and a single‑player campaign, all supported by detailed statistics and replay options.

01 / THE GUIDE

Disease Types

Ten distinct pathogen categories range from bacteria to bio‑weapons, mind control, and zombies. Each type requires a unique evolutionary strategy to overcome human defenses.

Choosing a disease influences the available evolutions, abilities, and genes, shaping how you spread infection and respond to cure efforts.

  • Experiment with different types to discover varied playstyles.
  • Match disease strengths to scenario challenges for better success.

02 / THE GUIDE

Scenarios

Twenty‑three unique scenarios add specific challenges, such as a new Swine Flu strain or an Ice Age setting. Scenarios alter world conditions and government responses.

Adapting your strategy to each scenario’s constraints is essential for achieving global domination.

  • Read scenario briefings before evolving.
  • Prioritize traits that counter the scenario’s specific obstacles.
Plague Inc: Evolved official gameplay screenshot
Publisher-provided gameplay image · Ndemic Creations

03 / THE GUIDE

Multiplayer Modes

Competitive PvP pits two plagues against each other for genetic dominance, while cooperative co‑op lets two players combine diseases to overwhelm humanity.

Both modes feature new evolutions, abilities, and genes to help players outmaneuver each other and the world’s cure efforts.

  • Coordinate with your co‑op partner to cover complementary infection routes.
  • In PvP, monitor your opponent’s progress and adjust evolutions accordingly.

04 / THE GUIDE

Content Creation

The Contagious Content Creator provides tools for designing custom scenarios, new plague types, worlds, and events. Creations can be shared through Steam Workshop.

Over 10,000 community scenarios are already available, offering fresh challenges beyond the base game.

  • Use the editor’s templates to speed up scenario building.
  • Test your custom scenario in single‑player before publishing.

05 / THE GUIDE

Visuals and Statistics

Full 3D disease models, city‑cam views, and organ‑by‑organ body scanners deliver detailed visual feedback. Stats and graphs track infection, death, government reaction, and cure progress.

Game replays let you review performance, and features like speed runs and Mega‑Brutal difficulty add further depth.

  • Watch the body scanner to identify which organs need targeting.
  • Analyze cure graphs to anticipate when to shift evolution focus.

WATCH THE GAME

Plague Inc: Evolved videos

Official trailers & gameplay

INSIDE THE WORLD

Screenshots & game images

5 official screenshots

IN THIS WIKI

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COMMUNITY

Player discussion

    QUICK ANSWERS

    Plague Inc: Evolved FAQ

    Can I play Plague Inc: Evolved without a mouse?

    Yes, the game includes a mouse‑only option and can be played without timed input.

    Is there a way to share custom scenarios with other players?

    Custom scenarios can be uploaded to Steam Workshop, where the community can download and play them.

    What platforms support the game?

    Plague Inc: Evolved runs on Windows, macOS, and Linux computers.

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    SOURCES & CREDITS

    Official resources and further reading

    Original editorial guidance. Game imagery and trailers are provided by the publisher through Steam. Media and reference links checked 2026-10-22. Game versions, supported platforms, and balance can change; consult the linked release notes for current details.