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About Destroy All Humans! 2 - Reprobed
Destroy All Humans! 2 – Reprobed returns Crypto to the swinging 1960s, armed with classic weapons and new tech like the Meteor Shower. The alien invader seeks revenge on the KGB while forging uneasy alliances with humanity.
The game offers a larger, open‑world Earth to roam, DNA‑based skill upgrades, and a local two‑player split‑screen co‑op mode that lets a friend experience the full story alongside you.
01 / THE GUIDE
1960s Earth and KGB Conflict
The narrative places Crypto in a chemically‑induced 1960s America, where the KGB is responsible for destroying his mothership. This backdrop drives the revenge motive and the need to interact with various human groups. The setting encourages players to explore a stylized version of Mother Earth, encountering both hippie culture and Cold War tensions as part of the storyline.
- Observe how period‑specific details influence mission objectives.
- Compare the KGB’s role here with its portrayal in the original title.
02 / THE GUIDE
Classic Weapons and New Tech
Players can wield classic alien armaments while also accessing new technology such as the Meteor Shower. These tools are used to dominate human opposition and complete objectives. The inclusion of both familiar and fresh weaponry expands combat options without altering the core alien‑versus‑human premise.
- Test the Meteor Shower in open areas for maximum effect.
- Balance classic weapons with new tech to manage different enemy types.

03 / THE GUIDE
Larger Open World
Reprobed features a much larger, more open world than its predecessor, allowing players to roam 1960s cities and countryside. This expanded map supports varied missions and side activities. Exploration is encouraged through the ability to “hoover up” humans from multiple countries, integrating geography into progression.
- Map out key locations before committing to a mission.
- Use the open world to locate diverse human populations for DNA collection.
04 / THE GUIDE
Local Two‑Player Split‑Screen Co‑op
The game supports shared split‑screen co‑op, letting a second player join the adventure locally. Both participants experience the full story together, rather than a limited mode. This feature is built on the game’s existing single‑player framework, extending it to a cooperative experience without altering narrative content.
- Coordinate with your partner on weapon choices for balanced play.
- Coordinate with your partner early so both players can follow the shared split-screen view clearly.
05 / THE GUIDE
Human Harvesting and DNA Cocktails
Players can harvest humans from various nations and grind them into DNA cocktails, which are then used to upgrade Crypto’s abilities. This mechanic ties progression directly to world interaction. The system encourages players to seek out diverse populations, linking exploration with skill development.
- Prioritize harvesting in densely populated areas for faster upgrades.
- Compare the effects of different DNA cocktails to find the most useful upgrades.





COMMUNITY
Player discussion