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About CURE - A Hospital Simulator
CURE puts you and up to six friends in charge of an overnight Emergency Room as the apocalypse begins. You must diagnose bizarre symptoms, treat patients, and keep the hospital running while chaos erupts outside. The game blends first‑person action with strategic management, letting you expand, upgrade, and decorate your facility as you survive night after night.
A unique Shoutout Engine links your live stream to the game, allowing Twitch viewers to become patient NPCs and influence outcomes. This hybrid of simulation and action encourages teamwork, fast decision‑making, and creative hospital design while unlocking new medicines, tools, weapons, and story insights as you progress.
01 / THE GUIDE
Nightshift Co‑op Play
The game supports co‑op with you and up to six friends, meaning up to seven players can share responsibilities such as triage, treatment, and supply ordering during a single nightshift. Teamwork is essential because each player experiences the chaotic first‑person environment simultaneously.
All participants operate under a shared budget, so coordinated ordering of supplies and division of tasks directly affect how well the hospital can handle the influx of patients and any external threats that appear during the night.
- Assign clear roles at the start—one player can focus on supplies while another handles triage.
- Use voice chat to coordinate quickly when new patients arrive.
02 / THE GUIDE
Diagnostic Tools & Unconventional Treatments
Players diagnose patients using a variety of interactive tools that become more varied as the apocalypse unfolds, leading to increasingly strange symptoms that must be identified and treated.
The game notes that sometimes you must apply “the right amount of harm,” balancing the oath to do no harm with the desperate need for unconventional treatments in extreme situations.
- Observe visual cues that hint at quarantine needs versus standard care.
- Try different tools as new symptoms appear to discover the most efficient cures.

03 / THE GUIDE
Strategic Hospital Management
Beyond treating patients, you must order supplies, manage a budget, and expand the facility. Upgrading equipment and decorating the space are part of building the “hospital of your dreams.”
Effective management reduces chaos, allowing faster treatment and better survival rates as nights progress, while the budget constraints force prioritisation of essential items over cosmetic upgrades.
- Prioritise essential medical equipment before cosmetic upgrades.
- Track inventory regularly to avoid shortages during peak patient influx.
04 / THE GUIDE
Twitch & Discord Integration
CURE’s Shoutout Engine connects live streams directly to the game, letting audience members become patient NPCs whose actions can affect the flow of each night.
This integration adds an interactive layer where viewers participate as patient NPCs and can influence the game, creating a more engaging streaming experience.
- Set clear rules for audience participation to keep gameplay balanced.
- Encourage viewers to suggest unconventional treatments for added variety.
05 / THE GUIDE
Progression & Unlocks
Surviving more nights and saving patients unlocks new medicines, diagnostic tools, weapons, and story insights, expanding the options available for treating increasingly bizarre illnesses.
Each unlock provides additional strategic choices, encouraging players to adapt their hospital layout and treatment approaches as the apocalypse intensifies.
- Focus on unlocking diagnostic tools early to handle strange symptoms efficiently.
- Review story insights for clues about upcoming patient challenges.





COMMUNITY
Player discussion