GameWiki.
CURE - A Hospital Simulator official game artwork

THE GAME WIKI

CURE - A Hospital Simulator Wiki

Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator

Steam ↗Windows
GameWiki EditorialReviewed 5 guide topics

GET YOUR BEARINGS

About CURE - A Hospital Simulator

CURE puts you and up to six friends in charge of an overnight Emergency Room as the apocalypse begins. You must diagnose bizarre symptoms, treat patients, and keep the hospital running while chaos erupts outside. The game blends first‑person action with strategic management, letting you expand, upgrade, and decorate your facility as you survive night after night.

A unique Shoutout Engine links your live stream to the game, allowing Twitch viewers to become patient NPCs and influence outcomes. This hybrid of simulation and action encourages teamwork, fast decision‑making, and creative hospital design while unlocking new medicines, tools, weapons, and story insights as you progress.

01 / THE GUIDE

Nightshift Co‑op Play

The game supports co‑op with you and up to six friends, meaning up to seven players can share responsibilities such as triage, treatment, and supply ordering during a single nightshift. Teamwork is essential because each player experiences the chaotic first‑person environment simultaneously.

All participants operate under a shared budget, so coordinated ordering of supplies and division of tasks directly affect how well the hospital can handle the influx of patients and any external threats that appear during the night.

  • Assign clear roles at the start—one player can focus on supplies while another handles triage.
  • Use voice chat to coordinate quickly when new patients arrive.

02 / THE GUIDE

Diagnostic Tools & Unconventional Treatments

Players diagnose patients using a variety of interactive tools that become more varied as the apocalypse unfolds, leading to increasingly strange symptoms that must be identified and treated.

The game notes that sometimes you must apply “the right amount of harm,” balancing the oath to do no harm with the desperate need for unconventional treatments in extreme situations.

  • Observe visual cues that hint at quarantine needs versus standard care.
  • Try different tools as new symptoms appear to discover the most efficient cures.
CURE - A Hospital Simulator official gameplay screenshot
Publisher-provided gameplay image · Sentinel Games

03 / THE GUIDE

Strategic Hospital Management

Beyond treating patients, you must order supplies, manage a budget, and expand the facility. Upgrading equipment and decorating the space are part of building the “hospital of your dreams.”

Effective management reduces chaos, allowing faster treatment and better survival rates as nights progress, while the budget constraints force prioritisation of essential items over cosmetic upgrades.

  • Prioritise essential medical equipment before cosmetic upgrades.
  • Track inventory regularly to avoid shortages during peak patient influx.

04 / THE GUIDE

Twitch & Discord Integration

CURE’s Shoutout Engine connects live streams directly to the game, letting audience members become patient NPCs whose actions can affect the flow of each night.

This integration adds an interactive layer where viewers participate as patient NPCs and can influence the game, creating a more engaging streaming experience.

  • Set clear rules for audience participation to keep gameplay balanced.
  • Encourage viewers to suggest unconventional treatments for added variety.

05 / THE GUIDE

Progression & Unlocks

Surviving more nights and saving patients unlocks new medicines, diagnostic tools, weapons, and story insights, expanding the options available for treating increasingly bizarre illnesses.

Each unlock provides additional strategic choices, encouraging players to adapt their hospital layout and treatment approaches as the apocalypse intensifies.

  • Focus on unlocking diagnostic tools early to handle strange symptoms efficiently.
  • Review story insights for clues about upcoming patient challenges.

WATCH THE GAME

CURE - A Hospital Simulator videos

Official trailers & gameplay

INSIDE THE WORLD

Screenshots & game images

5 official screenshots

IN THIS WIKI

Your reading checklist

0 of 6 complete

COMMUNITY

Player discussion

    QUICK ANSWERS

    CURE - A Hospital Simulator FAQ

    Can CURE be played alone or only with friends?

    The game offers both single‑player and multiplayer co‑op modes, allowing you to manage the nightshift solo or with up to six friends.

    Which operating systems does CURE support?

    CURE is listed for Windows; it is not listed for macOS or Linux in the official store information.

    How does the Twitch Shoutout Engine affect gameplay?

    It lets Twitch viewers become patient NPCs, influencing the game during live streams.

    More CURE - A Hospital Simulator guides

    SOURCES & CREDITS

    Official resources and further reading

    Original editorial guidance. Game imagery and trailers are provided by the publisher through Steam. Media and reference links checked 2026-10-23. Game versions, supported platforms, and balance can change; consult the linked release notes for current details.